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National News

Phase I trials are designed to assess the potential of new treatments that have never before been tested on humans and tend to focus on safety rather than effectiveness.

Cancer patients in early trials of treatments may have unrealistic expectations

Traditional culture methods take two to three days to identify bacteria and test their drug resistance from a urine sample

Hopes quicker urinary infection test will help fight against resistant superbugs

Monarch said it was 'trading well' and expected to make £40 million before tax and other deductions by the end of the financial year to October

Monarch Airlines denies rumours of financial crisis

The Duke and Duchess of Cambridge arrive by seaplane in Vancouver Harbour

Views mesmerise William and Kate on sea plane trip

The Smiler rollercoaster at Alton Towers

Alton Towers owner back in court over Smiler crash

Police investigating Ben's disappearance will begin excavation work on the Greek island of Kos on Monday

Ben Needham's mother tells of fears as dig begins at Kos site

Lord Blunkett said the re-election of Jeremy Corbyn as Labour leader was a 'catastrophe' for the party

Labour Party under Jeremy Corbyn not electable - Blunkett

Allies of Theresa May, pictured with then PM David Cameron, have denied claims she blocked plans to curb EU immigration into Britain

Theresa May argued for immigration brake, say allies

Boris Johnson triggered a furious response from Moscow after saying Russian forces may be guilty of war crimes in Syria

Anger at the UN as Russia and the West trade insults over Syria

Lord Mayor of London Jeffrey Mountevans and the Prince of Wales attend National Police Memorial Day

Officer attacks politicians over funding cuts and 'hollow' praise

Ben Needham disappeared 25 years ago

Ben Needham: police to begin new dig on Kos

The Earl of Wessex congratulates the Countess of Wessex, third left, with their children at the end of a 450-mile cycling challenge

Sophie's 450-mile cycling challenge ends in triumph at Buckingham Palace

(1)
Mary Berry will not jump ship to Channel 4 when Bake Off changes channels

Bake Off star Mary Berry dismisses retirement reports

The Foreign Secretary said Russian involvement was prolonging the Syrian conflict

Russia hits back at Johnson 'war crimes' slur

(2)
Jason Kenny and Laura Trott as they celebrate their wedding at Hilltop Country House in Cheshire. (Picture: Martin Gardner/Hilltop Country House)

Olympic golden couple Laura Trott and Jason Kenny tie the knot

Labour leader Jeremy Corbyn is interviewed by Andrew Marr for the BBC1 current affairs programme, The Andrew Marr Show, at the Museum of Liverpool before the start of the Labour Party annual conference.

Change or die, moderates warn Labour Party

(7)
Laurence Fox and Billie Piper were married for eight years

Laurence Fox tells of sleep loss and panic attacks since split with Billie Piper

Southern Railway workers are locked in a long running dispute over the role of conductors

Rail passengers face months of industrial conflict, warns union leader

Marc Anwar at last year's British Soap Awards

Coronation Street star sacked over 'unacceptable' comments about Indian people

(11)
Peter Tobin has been convicted of three murders but is suspected of having committed more

Serial killer Peter Tobin definitely left other victims, detective says

Ryanair boss Michael O'Leary accused the Government of delaying decision-making on Brexit

City chiefs slam PM's Brexit stance

(12)
The report called on the Health Secretary to make retention of older GPs as much of a priority as recruitment

NHS risks 'brain drain' if older GPs are not retained, report warns

Jeremy Corbyn said concerns about continuing with the post-Brexit free movement of people could be tackled with a fund backing areas under pressure and action against undercutting local wages

Jeremy Corbyn warns against 'hard Brexit' due to manufacturing impact concerns

(2)
Mary Berry is staying with the BBC

Grilling for TV chiefs over bunfight for rights to The Great British Bake Off

(1)
Zoe Ball and Norman Cook are separating

Zoe Ball and husband Norman Cook announce separation 'with great sadness'

(2)
Police divers searching for a missing 14-year-old boy found a body in the River Erewash in Stapleford, near Nottingham

Body found after police called following reports of boy, 14, in river

Pippa acting as bridesmaid to William and Kate

Man held after claims Pippa Middleton's account was hacked

Yvette Cooper said one Twitter user wanted to 'behead' her

Yvette Cooper: I've received online death threats

(5)
Jeremy Corbyn said he now wants to concentrate on setting out policies on how Labour planned to achieve social justice

Jeremy Corbyn to focus on education and bringing Labour together

(9)
The Duke and Duchess of Cambridge arrive by seaplane in Vancouver

Views mesmerise William and Kate on sea plane trip

(5)
Tony Blair said the process looking into claims should never have been set up

Corbyn backs UK troops probe following Blair criticism

(4)
Theresa May failed to support David Cameron, pictured, on 13 separate occasions, according to Sir Craig Oliver

Theresa May allies deny PM 'let down' David Cameron over EU vote

(1)
Junior doctors have suspended planned strike action

Suspension of junior doctors' strike action welcomed by Department of Health

Jones, 74, directed Monty Python's Life of Brian and Monty Python's The Meaning of Life

Dementia impact on Monty Python's Terry Jones 'painful to watch', says Palin

Zoe Ball and Norman Cook are separating

Zoe Ball and husband Norman Cook announce separation 'with great sadness'

(1)
Luke Jones, 25, was released on licence on September 16 (Greater Manchester Police/PA)

Police launch manhunt in Manchester after rapist released on licence disappears

Charlie Elphicke said: "We must act now to catch and jail these criminals - and end their evil trade of modern slavery."

Dover MP calls for new patrol force after police detain three suspected migrants

Police attended the scene and recovered a body

Body found after police called following reports of boy, 14, in river

Pippa acting as bridesmaid to William and Kate

Man held after claims Pippa Middleton's account was hacked

(6)
Ken Loach spoke of his fears of a Donald Trump presidency

Ken Loach backing Jeremy Corbyn to stand up to state's 'abusive behaviour'

Campaigners signalled that a second Scottish independence poll could be called once a broad outline of the UK's Brexit measures emerges

Sturgeon 'could call second Scottish independence referendum in autumn 2017'

(25)
Junior doctors have suspended planned strike action

Suspension of junior doctors' strike action welcomed by Department of Health

Jeremy Corbyn celebrates his victory following the announcement

Jeremy Corbyn looks to rebuild team following re-election as Labour leader

(30)
Three people have been held in connection with the discovery

Man with UK passport charged in Thailand over body-in-freezer

Defence Secretary Sir Michael Fallon said the operation to take the city of Mosul would begin 'in the next few weeks'

Forces 'on the cusp' of taking last major Islamic State stronghold in Iraq

(6)
EU rules currently forbids the testing of European doctors coming to work in the UK

Brexit could pave way for tougher checks on European doctors

(19)
A break-in at a Stoke-on-Trent shopping centre netted a £400,000 haul of high-value watches

Five men charged after £400,000 watches haul from Potteries break-in

Sarah Champion is her party's spokeswoman on domestic abuse

Jeremy Corbyn backs Sarah Champion who admits she 'lost control' in domestic row

(8)
The work is by Neoclassical painter Sir Lawrence Alma-Tadema

Victorian masterpiece's rediscovery has 'stunned the art world'

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