The A342 is closed between the junction with the A4 and the Lansdowne Arms after a crash this morning.
Police were called to the incident at 8.53am after involving a black Mitsubishi and a blue Renault Megane crashed.
Ambulance services were called and paramedics treated two casualties, both with minor injuries, at the scene.
The road was blocked due to debris.
Anyone with information should call 101 or Crimestoppers on 0800 555 111, where details can be left anonymously.
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