Children from two year groups at Kingsbury Green Academy are self-isolating.
The school made the decision after seven students received a positive covid-19 test and issued an email to parents.
Jason Tudor, headteacher at Kingsbury Green Academy, said: "I can confirm that three students in Year 10 and four students in Year 7 have received a positive Covid-19 test result and so all students from those two year groups have been asked to remain at home and self-isolate.
“They must continue to self-isolate for ten days, after which each student will need to test negative for Covid-19 before they can return to the school.”
The students will now need to self isolate until June 28.
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